Researchers examined men diagnosed
with premalignant prostate cancer lesions: specifically, high-grade
intraepithelial neoplasia (HGPIN) or atypical small acinar proliferation
(ASAP). Men diagnosed with HGPIN have prostate gland cells that exhibit abnormal
patterns (like cancer cells would). Men with ASAP have a collection of lesions
on the prostate that cannot be definitively diagnosed as malignant or benign.
The men were randomized into two
groups. For one year, 48 men took a placebo pill twice a day, and 49 men took a
200 mgs green tea capsule called Polyphenon E twice a day. At the end of
the year there was no statistical difference in prostate cancer cases diagnosed
between the two groups, however, prostate cancer development seemed to be
significantly suppressed in the group supplementing with Polyphenon E.
Men diagnosed with only HPIN at the
start of the study had a lower combined rate of ASAP and prostate cancer
development when taking green tea capsules. The catechins in green tea,
primarily EGCG, also lowered prostate-specific antigen (PSA) levels, an
indicator of prostate cancer. There were no reported side effects in men taking
the 200 mgs capsules.
Another win for green tea…and
another reason to drink a cup every day!
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