All chili
peppers, including cayenne, contain a substance called capsaicin, a
natural analgesic that may help relieve arthritis pain
, research shows.
A gel with 0.0125% capsaicin was an effective treatment in mild to moderate osteoarthritis pain in knees, according to a study published in a 2010 issue of the Journal of the Medical Association of Thailand.
“The exact mechanism is unknown and being studied, but it’s believed that capsaicin relieves pain
and itching by acting on sensory nerves,” says Dr.
Lewis. “[It] depletes or interferes with substance P, a naturally produced
chemical involved in transmitting pain impulses to the brain.”
Without neurotransmitters, pain signals can no longer be sent to joints.
“The amount of capsaicin determines how long relief lasts, and the effect is temporary,” Dr. Lewis advises. “The hotter the pepper, the more capsaicin it contains.”
Eating hot peppers also causes the release of endorphins, hormones released in the body that produce a feeling of well-being, which act as the body’s own pain medication.

A gel with 0.0125% capsaicin was an effective treatment in mild to moderate osteoarthritis pain in knees, according to a study published in a 2010 issue of the Journal of the Medical Association of Thailand.
“The exact mechanism is unknown and being studied, but it’s believed that capsaicin relieves pain

Without neurotransmitters, pain signals can no longer be sent to joints.
“The amount of capsaicin determines how long relief lasts, and the effect is temporary,” Dr. Lewis advises. “The hotter the pepper, the more capsaicin it contains.”
Eating hot peppers also causes the release of endorphins, hormones released in the body that produce a feeling of well-being, which act as the body’s own pain medication.
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